I voted for A. Here are my thoughts about the various options.
Option A: This one is the most obvious good one: you score points, get a meeple back, and place a meeple, all of which are good. The "get a meeple back" value is low, because you have only 1 meeple in play in a 4-player game, so meeples aren't critical. Downside is that the possible field connection from a tile at [-2;-1] will make a very valuable farm that could be grabbed by an opponent.
Option B: This is a close second for me. As many others have argued, after placing this tile, the field is getting big. As @Bumsakalaka points out, the field is also not super easy to invade, because of the road across the bottom. But an opponent could glom on with a tile at [4;-2] having a road on the west edge, ensuring connection with any tile at [3;-2], or by playing at [-3;0] and then completing the loop at [-2;-1]. Also, at the moment the tile is placed, there are only 2 completed cities and ALL of the CCCx tiles are still out, so the city caps that we hope will be completed are not a sure thing.
Option D: I think this has real merit. I actually like getting another meeple on the board, in a position that would be allow placement of the CCCC tile reasonably early in the game. Of course it also opens the possibility of trapping Gray and Red with any FFxx tile. In a 3-player game, I would probably choose this as my first choice, because the trap has a higher value if there is no untrapped opponent.
Option C: Similar idea to D, but I always feel like going for a glom that requires 2 tiles in an already crowded area of the landscape ends up backfiring with my meeple getting trapped or stuck for a long time.
I found the choices and discussion to be very interesting and really enjoyed the nearly even split between A and B. The fact that so many chose B and no one chose C nor D reflects concrete realization of two of
@danisthirsy's general tips for 4-player games (a great read, by the way):
2) "The early farmer wins the field"
...
5) "The questionable importance of blocking"
Thanks everyone for voting and commenting.
Next week will be a further continuation of this game...
Again, please message me with photos from your own games or just ideas of interesting ideas for problems...