Hi sgbea13,
Welcome to the forum and congrats for your first post!
Hope you enjoy all the stuff you may find here.
Regarding your question, misalignment in tiles is not a common thing but you can find it from tile to time.
I have a misaligned copy of C1 German Cathedrals (see attachment) that you can notice clearly due to the symbol on the tile. Some positions of the tiles also show the misalignment too.
Cheers!